This dataset is acquired from China Earthquake Networks Center by data crawl, which specifically describes some earthquake information about time, latitude, longitude, depth, magnitude, the disaster scope, the degree of damage, death toll et al. And the dataset counts the earthquake event occurred in Qinghai-Tibet Plateau from 1990 to 2015, which includes 161 data in total. This dataset can give users the information of temporal and spatial distribution of earthquake occurrence, provide a base data for earthquake prevention research in the area, and enrich the disaster prevention and mitigation knowledge service system data content.